Nonlinear Optics in Biomedical Engineering

My research is based on the interactions of light and matter, and its use for biomedical applications. These interactions range from the use of light to pattern biomaterials to optical tweezers, in which the electric fields of tightly focussed laser light can apply appreciable forces to microscopic materials: cells in culture or microspheres used as probes of the stiffness and viscoelastic response of extracellular matrix. This enable us to non-invasively probe the effects of mechanical stimuli.

 
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Optical Tweezers

micromechanical manipulation and sensing

2 micron diameter bead periodically forced in extracellular matrix by near infrared optical tweezer

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Azosilk

applying nonlinear optics to biomaterials

40 micron width features written in azosilk film using ultrafast laser

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Medical Instrument Design

teaching practical instrument design

Labview block diagram for ECG computer interface